Vilitra 60mg can be taken with water. Simply remove one Vilitra 60mg tablet from its blister pack and swallow it with water. If you have difficulty swallowing, consult your doctor; a change in treatment may be considered. To avoid side effects, avoid alcohol and grapefruit juice while taking this medication. Also, avoid using hallucinogenic drugs. The advantage of vardenafil is that its effect lasts between 8 and 10 hours, which is 50% longer than a standard dose of sildenafil. The drug’s mechanism of action begins with blocking the PDE-5 enzyme in the body. This typically leads to the formation of another substance called cGMP. This substance activates nitric oxide in the blood vessels, causing the arterial walls to relax. Blood flow to the p*nis and surrounding tissues then increases. Once the penis is stimulated, an erection occurs.