Isotretinoin is a powerful oral medication widely prescribed for treating severe acne that doesn’t respond to conventional therapies. It works by reducing the production of sebum (oil) in the skin, which helps prevent clogged pores, bacterial growth, and recurring breakouts. For many patients, a full course of isotretinoin provides long-term or even permanent improvement, making it one of the most effective solutions for stubborn acne. However, because of its strong effects, it must only be taken under a doctor’s supervision. While isotretinoin offers life-changing benefits, it can also have side effects such as dry skin, chapped lips, or, in rare cases, liver and mood-related issues. Pregnant women should avoid this medication as it may cause serious birth defects. Regular check-ups, blood tests, and following a healthy lifestyle alongside treatment are essential for safe use. With proper guidance, isotretinoin can be a game-changer for achieving clear, healthy skin.