The fastest ways to stop wheezing may vary depending on the underlying cause. If you have asthma and have a reliever inhaler, you need to use it as directed on your asthma action plan or as prescribed by your doctor. Reliever medications make breathing easier. While dealing with mild wheezing: Sit upright rather than lying flat. Breathe slowly and deeply at a steady rate. Avoid smoke, dust, strong smells, or an identified cause. Use prescribed respiratory medication exactly as directed. Consult GP Glenroy at Magnus Medical if the wheezing is new, continuous, recurrent, or worsens. Avoid using home remedies to treat breathlessness.